Shopping Cart
- Remove All
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $116 | In Stock | |
5 mg | $289 | In Stock | |
10 mg | $478 | In Stock | |
25 mg | $789 | In Stock | |
50 mg | $1,080 | In Stock | |
100 mg | $1,480 | In Stock | |
500 mg | $2,970 | In Stock | |
1 mL x 10 mM (in DMSO) | $295 | In Stock |
Description | ATX inhibitor 5 is a potent and orally active autotaxin (ATX) inhibitor (IC50 : 15.3 nM) that reduces the level of CCl4-induced hepatic fibrosis and has anti-hepatic fibrosis effects,. |
In vitro | ATX inhibitor 5 (10 μM) successfully suppresses collagen content induced by TGF-β.[1] |
In vivo | ATX inhibitor 5 (20-40 mg/kg/d; p.o.; two weeks) prominently decreases CCl4-induced hepatic fibrosis levels.[1] |
Molecular Weight | 474.87 |
Formula | C22H18ClF3N6O |
Cas No. | 2402772-45-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 225.0 mg/mL (473.8 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
|
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.